Department of Life Science Informatics and Data Science, B-IT, LIMES Program Unit Chemical Biology and Medicinal Chemistry, Rheinische Friedrich-Wilhelms-Universität, Friedrich-Hirzebruch-Allee 5/6, ...

MEK mitogen-activated protein kinase kinase, MT mutant, Pi inorganic phosphate, P13K phosphoinositide 3-kinase, PLCε phospholipase Cε, RALGDS Ral guanine nucleotide dissociation stimulator ...

In a report released today, Graig Suvannavejh from Mizuho Securities reiterated a Buy rating on Verastem (VSTM – Research Report), with a price ...

Scorpion would spin out its non-phosphoinositide 3-kinase alpha pipeline assets into a new company that would be owned by Scorpion's existing shareholders, with Lilly retaining a minority interest.

In some cases, the ketogenic diet made the anticancer drugs phosphoinositide 3-kinase inhibitors (PI3K inhibitors) work more effectively. This effect was partly attributed to the fact that the ...

For example, mutations in proteins of the PI3K–mTOR (phosphoinositide 3-kinase–mammalian target of rapamycin) pathway — which is commonly activated in cancer — have been shown to drive ...

Key Laboratory of Industrial Microbiology, Ministry of Education, Tianjin Industrial Microbiology Key Laboratory, College of Biotechnology Tianjin University of Science and Technology, Tianjin ...

Such pathways included those that were related to hypoxia, including PTEN (phosphatase and tensin homolog), PI3K (phosphoinositide 3-kinase), and MAPK (mitogen-activated protein kinase) signaling. WNT ...

The DYRK1A enzyme is a pivotal contributor to frequent and severe episodes of otitis media in Down syndrome, positioning it as a promising target for therapeutic interventions.

In this Healio Video Perspective from Retina 2025, Peter K. Kaiser, MD, of Ocular Therapeutix, discusses positive data for ...