Zodasiran targets ANGPLT3, an emerging therapeutic target to treat HoFH and other dyslipidemias – YOSEMITE Phase 3 study further enhances Arrowhead’s late-stage pipeline o ...

Broiler chickens, bred for rapid growth, accumulate more fat under chronic heat stress, which reduces meat quality and ...

Abstract Abstract Lipoprotein lipase (LPL) induces macrophage tumor necrosis factor-α (TNF-α) gene expression and protein secretion. Since TNF-α can increase interferon gamma (IFN-γ)–dependent nitric ...

This study aimed to determine to what extent variants of lipoprotein lipase (LPL) might interact with birth weight or body weight in determining the lipid profile concentrations in children and ...

Medically reviewed by Josephine Hessert, DO Walking can help lower your cholesterol when done regularly and at a brisk pace. A 2022 study reported that moderate-intensity exercise, such as brisk ...

Herein, we discuss the genetic determinants of lipoprotein (a) levels, explore the pathophysiological mechanisms underlying the association between lipoprotein (a) and cardiovascular disease, and ...

Access to the active site of human pancreatic lipase (HPL) is controlled by a surface loop (the lid) that undergoes a conformational change in the presence of amphiphiles and lipid substrate. The ...

Lipoprotein lipase (LPL) is a dimeric enzyme that is responsible for clearing triglyceride-rich lipoproteins from the blood. Although LPL plays a key role in cardiovascular health, an experimentally ...

Potential drugs targeting LPL offer new candidates for precision treatment of DKD. These findings lay a theoretical foundation for understanding the molecular mechanisms of DKD and developing ...