Zodasiran targets ANGPLT3, an emerging therapeutic target to treat HoFH and other dyslipidemias – YOSEMITE Phase 3 study further enhances Arrowhead’s late-stage pipeline o ...

Broiler chickens, bred for rapid growth, accumulate more fat under chronic heat stress, which reduces meat quality and ...

Medically reviewed by Josephine Hessert, DO Walking can help lower your cholesterol when done regularly and at a brisk pace. A 2022 study reported that moderate-intensity exercise, such as brisk ...

What Causes Familial Hyperchylomicronemia Syndrome? FCS happens because of a mutation in certain genes related to an enzyme called lipoprotein lipase (LpL). You have to get the mutated gene from ...

image: Lipoprotein lipase (LPL) mediates peripheral tissue triglyceride (TG) uptake. view more Credit: Yiliang Zhang, Shengyang Zhou, Runming Zhao, Yingzhen Huang, Yan Wang Living organisms store ...

ANGPTL3 blocks LPL and blocks endothelial lipase. And the evinacumab disinhibits that. What does LPL do? Lipoprotein lipase is responsible for triglyceride metabolism primarily.

Lysosomal acid lipase deficiency (LAL-D) is part of a group of disorders known as lysosomal storage diseases. The disease tends to have its onset in childhood. Patients usually suffer from progressive ...

Upregulation of one gene in particular—lipoprotein lipase (Lpl)—explained much of the enhanced lipid processing in response to the HK2 blockade. Primarily expressed by microglia in the brain, lpl ...