A 19-year-old woman with a history of depression and anxiety symptoms was admitted to the hospital because of seizure, ...

This Double Take video explores the link between certain strains of human papillomavirus and cancer and reviews the evidence ...

A 71-year-old woman with systemic lupus erythematosus presented to the ophthalmology clinic for an annual screening examination for hydroxychloroquine-related toxic effects. She reported no vision ...

After a year of clinical rotations in which a medical student learns to face death up close, her experience on a silent meditation retreat provides her with new perspective on death and life.

The author describes the implementation of a clinical-care program involving pronuclear transfer to minimize the transmission of mitochondrial disease. He also describes the long pathway leading to ...

Cardiac allotransplantation is warranted in children with end-stage heart failure or irreparable congenital heart disease. A dearth of organs for transplantation has contributed to long wait-list t ...

Real-world data could help advance disease prevention and treatment, enhance quality of care, and empower patients to improve their health. But various challenges continue to impede their utilization.

The author describes pronuclear transfer, a type of mitochondrial donation, which was made available to women with mitochondrial DNA disease in a reproductive care pathway implemented in Newcastle, ...

When someone is declared brain-dead during pregnancy, state laws regarding abortion, advance directives, and end-of-life care may all come into play. What should the deciding factors be?

To the Editor: In the API-CAT trial (April 10 issue),1 Mahé and colleagues confirm that a reduced dose of apixaban (2.5 mg twice daily) is noninferior to a full dose (5.0 mg) of the drug for ...

Audio Interview from the New England Journal of Medicine — Interview with Katie Watson on the interaction of abortion laws with advance-directive and end-of-life laws.

We offered mitochondrial donation (by pronuclear transfer) or preimplantation genetic testing (PGT) to a series of women with pathogenic mtDNA variants who sought to reduce the transmission of ...