Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...
Objective To determine whether proton pump inhibitors (PPIs) are associated with an increased risk of colorectal cancer, compared with histamine-2 receptor antagonists (H2RAs). Design The United ...
Background Patients with type 2 diabetes mellitus (T2DM) have higher pancreatic cancer (PC) risk. While aspirin has chemopreventive effects on digestive cancers, its effect on PC among patients with ...
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Mrs K Cauch-Dudek, Toronto Hospital, Western Division, 399 Bathurst St, West Wing 4–833, Toronto, Ontario M5T 2S8, Canada. Background—Fatigue is a frequent and debilitating symptom in patients with ...
Background: Three large randomised trials have shown that screening for colorectal cancer using faecal occult blood (FOB) tests can reduce the mortality from this disease. Two national pilot studies ...
2 Microbiology and Tumour Biology Centre, Karolinska Institute, Stockholm, Sweden 3 Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden 4 Microbiology and Tumour ...
Correspondence to: Dr M Prince, Centre for Liver Research, 4th Floor William Leech Building, Newcastle University Medical School, Framlington Place, Newcastle NE2 4HH, UK; Martin.prince{at}ncl.ac.uk ...
Functional dyspepsia is a symptom complex characterised by postprandial upper abdominal discomfort or pain, early satiety, nausea, vomiting, abdominal distension, bloating, and anorexia in the absence ...
Background—The aetiology and pathology of both idiopathic megarectum and idiopathic megacolon are unknown. In particular, it is unknown whether there are abnormalities involving enteric nerves or ...
In the past few years, optical magnification endoscopy and chromoscopy have gained renewed interest in the West as a means for the early detection of minute lesions in patients with Barrett’s ...
Professor M A Fujino, First Department of Medicine, Yamanashi Medical University, 1110 Shimokato, Tamaho-cho, Nakakoma-gun, Yamanashi 409-38, Japan. BACKGROUND/AIMS The characteristics of pepsinogen ...