Xeroderma pigmentosum (XP) is a rare genetic disease that affects young children. These young patients, called children of the Moon, exhibit extreme sensitivity to ultraviolet (UV) rays and an ...

Five of the conditions (xeroderma pigmentosum, Cockayne's syndrome, trichothiodystrophy, Down syndrome, and triple-A syndrome) display a defect in the nucleotide excision repair pathway ...

The native structure of genomic DNA can be damaged in many ways, both by external agents and from within the cell as a consequence of normal metabolism In an effort to maintain their genomic ...

With $200 million of cash on hand, Clinuvel's financial position is the envy of other biotechs. But not everyone is happy.

as medicinal therapies to treat a range of severe disorders, including vitiligo, variegate porphyria, xeroderma pigmentosum, arterial ischaemic stroke, DNA repair, Parkinson's disease and more.

Meanwhile, Clinuvel has other earlier stage programs, including for xeroderma pigmentosum (a hereditary condition leading to a very high risk of skin cancer and other medical problems).

Other risk factors for melanoma include: existing moles pale skin, freckles, and light hair a family or personal history of melanoma xeroderma pigmentosum, a rare genetic disorder that leads to an ...

In that way, the NER machinery can adapt and change its shape depending on the task at hand. In the first stage, the NER protein XPC (xeroderma pigmentosum group C) acts like a first responder that ...

Window tinting can give drivers more privacy and protection from glare, but its practicality can also be a detriment to other ...