Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

"A key feature of NuFold is how it represents RNA internally, considering the base pairs that are pivotal to the structure while accurately capturing RNA's inherent flexibility. In benchmark tests ...

"A key feature of NuFold is how it represents RNA internally, considering the base pairs that are pivotal to the structure while accurately capturing RNA's inherent flexibility. In benchmark tests ...

Biologically active RNAs, including transport, ribosomal and small nuclear RNA (tRNA, rRNA, snRNAs) fold into unique structures guided by complementary pairing between nucleotide bases.

The “warm” data in the middle, such as your old photos, can take a few seconds to retrieve. Most data is cold, and a lot of ...

But real lightning would have struck infrequently—and mostly in open ocean, where organic compounds would have quickly ...

Assembling DNA nanostructures at more moderate temperatures opens up the possibility of using the structures in biomedical ...

The author is looking forward to seeing how Beam Therapeutics would do in their clinical trials of single-base DNA editing.

Armed with new proof-of-concept data showing that its in vivo base-editing therapy BEAM-302 can correct the gene mutation in ...

While initial study results suggest Beam's technology can correct alpha-1 antitrypsin deficiency's genetic roots, shares fell ...