The decision to terminate the HYPERION trial reflects a loss of clinical equipoise, making it unethical to continue the ...

Which of the statements below about the pathophysiology of fetal and neonatal alloimmune thrombocytopenia (FNAIT) are correct? Select one of the options for each question, then submit your answers to ...

Six centers will recruit up to 60 patients who will receive 200 mg of filgotinib once daily for 26 weeks. A new multicenter study has been launched to investigate the safety and efficacy of the Janus ...

In a situation where antibody testing is not available, high levels of CSF GFAP can be considered helpful for making a diagnosis and treating accordingly. Glial fibrillary acidic protein (GFAP) and ...

James Bussel, MD, is emeritus professor of pediatrics, medicine, and obstetrics and gynecology at Weill Cornell Medicine in New York City (Photo by Larry Luxner) Physicians currently treat pregnancies ...

Suppressive effects of JAK inhibitors have been demonstrated in various types of cells secreting proinflammatory cytokines and involved in the pathogenesis of allergic and autoimmune diseases. The ...

The prevalence of MS was greater in higher latitudes and to a lesser extent in countries with higher health care expenditures. The prevalence of multiple sclerosis (MS) is increasing globally, ...

ARC/CCL17 expression was significantly associated with histologically confirmed IgG4-RD, with 87.2% sensitivity and 84.6% specificity. A strong correlation between expression of TARC/CCL17 and ...

MScanFit motor unit number estimate could be a useful way of assessing the loss of motor axons in patients with chronic inflammatory demyelinating polyneuropathy (CIDP) correlating with clinical ...

Nineteen medications were identified that, when combined with avapritinib, may increase the risk of neuropsychiatric adverse events. Neuropsychiatric adverse events (AEs) may result from the use of ...

A total of 76% of the patients achieved 5-year survival and 30% experienced grade 3 or 4 infections. High-dose methotrexate (HD-MTX) with the modified Bonn protocol including intrathecal therapy is ...

A total of 15% of the patients analyzed had very early recurrence of pCCA and a poor prognosis. A new machine learning-based model has been developed to accurately identify patients’ risk of very ...