Learn about whether it’s possible to have MS without lesions. Often, an MRI of the brain or spinal cord can be useful in detecting areas of demyelination, as more than 90% of people with MS have ...

In the while matter of the brain a myriad of pinpoint lesions whose histologic appearance ... Review of experimental studies on etiology of human demyelinating diseases. In Proceedings of the ...

Multiple sclerosis, the prototype of demyelinating disease in man ... axon transection can occur in inflammatory lesions, and axonal loss is closely correlated with disease severity.

This leads to inflammation, loss of myelin, and formation of "lesions" or "plaques" within the brain tissue ... immune responses that lead to MS-like demyelination. One key player identified ...