Researchers harness the power of the world’s most advanced supercomputers to simulate the inner workings of cellular ...

In the first stage, the NER protein XPC (xeroderma pigmentosum group C) acts like a first responder that locates the site of the damaged DNA, or lesion, and then twists the DNA helix to make the ...

At risk individuals include: Transplant recipients (solid organ and stem cell) Genetic syndrome patients (Gorlin's, Rombo, Bazex, xeroderma pigmentosum, Muir-Torre) Lymphoma patients (non-Hodgkin ...

These disorders include ataxia-telangiectasia (AT), a degenerative motor condition caused by failure to repair oxidative damage in the cerebellum, and xeroderma pigmentosum (XP), a condition ...

Mutations in the XPF and XPG genes are known to cause nasty disorders like xeroderma pigmentosum, which makes sufferers highly susceptible to skin cancer, and Cockayne syndrome, which accelerates ...