Diagnosis of PDB is a combination of clinical evaluation, imaging and histopathological assessment. If an underlying cancer ...

When someone has Paget’s disease, it means the process of bone remodeling, which is the cycle of bone growth, has become abnormal. The result is that over time, bones can become larger, weaker ...

In Paget’s disease, the balance between bone removal and bone building gets disrupted. Bone building begins to occur at a faster pace than bone removal. The resulting new bone is brittle, weak ...