The familial chylomicronemia syndrome is a genetic disorder characterized by severe hypertriglyceridemia and recurrent pancreatitis due to a deficiency in lipoprotein lipase (LPL). Currently, there ...

The absence of intraluminal lipoprotein lipase prevents the lipolytic processing of triglyceride-rich lipoproteins and results in severe hypertriglyceridemia (chylomicronemia, defined as a ...

FCS happens because of a mutation in certain genes related to an enzyme called lipoprotein lipase (LpL). You have to get the mutated gene from both your parents to have the disorder.

What does LPL do? Lipoprotein lipase is responsible for triglyceride metabolism primarily. And we want to have more lipoprotein lipase activity to reduce severe hypertriglyceridemia.

Increasing HDL: Aerobic exercise stimulates the production of an enzyme called lipoprotein lipase (LPL), which raises HDL levels and breaks down fatty acids known as triglycerides that contribute ...

image: Lipoprotein lipase (LPL) mediates peripheral tissue triglyceride (TG) uptake. view more . Credit: Yiliang Zhang, Shengyang Zhou, Runming Zhao, Yingzhen Huang, Yan Wang ...

He has been one of the world leaders in understanding lipoprotein lipase (LPL) biology and pathophysiology and demonstrated that LPL activity was regulated by insulin in humans.

ANGPTL3 and ANGPTL8 are genetically validated targets for ASCVD and form the ANGPTL3/8 complex which is a potent endogenous inhibitor of lipoprotein lipase (LPL).