autosomal dominant tubulointerstitial kidney disease, focal segmental glomerulosclerosis, Alport syndrome, and atypical ...

Ten years ago doctors diagnosed Taff with Alport Syndrome. The disease damages the blood vessels in the kidneys. “It was rough, I didn’t have no energy, didn’t have no interest in anything.

It was also developing an miR-21 oligonucleotide called lademirsen for another genetic disease affecting the kidneys, Alport syndrome, but that was abandoned in 2022 and rights returned to Regulus ...