On a night where snow filled the air for all four quarters, the banged-up 49ers proved to be no match for a Super Bowl-contending Bills team that displayed a mastery of the conditions and their ...

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Watch safety Talanoa Hufanga's top highlights during his four seasons with the San Francisco 49ers. San Francisco 49ers tight end George Kittle catches a touchdown pass from Tampa Bay Buccaneers ...

Buffalo Bills and San Francisco 49ers reveal game-day inactives as both ... ball as they look to snap a two-game losing streak. With snow in the forecast and playoff seeding growing contentious ...

The 49ers’ cutthroat makeover of their roster isn’t a novel concept and they can only hope theirs springs success like those ...

Here's everything you need to know when the San Francisco 49ers play the Buffalo Bills Week 13 of the 2024 NFL season. Here's everything you need to know when the Kansas City Chiefs play the ...

The 49ers have reportedly granted Samuel permission to seek a trade, and the Buffalo Bills appear to be a reasonable destination for multiple reasons. The Bills need another proven weapon for ...

Buffalo Bills team reporter Maddy Glab joins 1st & 10 to breakdown the 49ers-Bills matchup, discuss what to expect on "SNF" and highlight key players to watch in the Week 13 contest. Breaking down ...

That's why Jarrett Bailey of The Sporting News projects the 49ers to trade Aiyuk to the Buffalo Bills in exchange for their fourth- and fifth-round picks. "Aiyuk is coming off an ACL injury ...